NYU Data Catalog

NYU Dataset

Authors: Stacy Loeb

Caitlin E. Curnyn

Angela Fagerlin

R. Scott Braithwaite

4 more author(s)...
Description: This dataset includes structured, in-depth interviews with 24 physicians from diverse clinical backgrounds and geographic areas within the United States. These physicians were identified with purposive sampling strategies. Physicians who reported currently caring for patients through active surveillance were invited to participate. An interview guide was developed based on a literature review and previous...
Subject: Cancer

Health Care System
Timeframe: 2015
Access Rights: Application Required

Author Approval Required

NYU Dataset

Authors: Florian Knoll

Patricia M. Johnson

Daniel K. Sodickson

Michael P. Recht

1 more author(s)...
Description: This deidentified imaging dataset is comprised of raw k-space data in several sub-dataset groups. Raw and DICOM data have been deidentified via conversion to the vendor-neutral ISMRMRD format and the RSNA Clinical Trial Processor, respectively. Manual inspection of each DICOM image was also performed to check for the presence of any unexpected protected health information (PHI), with spot checking...
Subject: Anatomy

Cancer
Access Rights: Free to All

Application Required

Alternate Title(s): PLCO
Description: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was a large randomized controlled trial that assessed whether certain screening practices decreased deaths from prostate, lung, colorectal and ovarian cancer. Approximately 155,000 men and women aged 55 to 74 years old were enrolled from 10 screening centers across the United States between November 1993 and July 2001. Participants...
Subject: Cancer

Chronic Disease

Health Care System
Access Rights: Application Required
Local Expert: Richard B. Hayes

NYU Dataset

Authors: Erica M. Briggs

Wilson McKerrow

Paolo Mita

Jef D. Boeke

2 more author(s)...
Description: Long interspersed element-1 (LINE-1) is an autonomous retroelement that utilizes copy and paste mechanism to propagate themselves throughout the genome through a process called retrotransposition. The LINE-1 bicistronic mRNA codes for two proteins, ORF1p and ORF2. While LINE-1 transcription is usually repressed in most healthy somatic cells, ORF1p expression has been observed in tumors, including prostate...
Subject: Cancer

Genomics
Access Rights: Free to All

NYU Dataset

Authors: Sophie E. Ruff

Nikita Vasilyev

Evgeny Nudler

Susan K. Logan

1 more author(s)...
Description: Previous study showed that PIM1 phosphorylates the androgen receptor (AR), the primary therapeutic target in prostate cancer. This study examined the mechanism how PIM1 phosphorylation of AR alters its transcriptional activity. They identified the AR co-activator, 14-3-3 ζ, as an endogenous PIM1 substrate in LNCaP cells. Rapid immunoprecipitation and mass spectrometry of endogenous proteins on chromatin...
Subject: Cancer

Genomics
Access Rights: Free to All

NYU Dataset

Authors: Russell J. Ledet

Sophie E. Ruff

Yu Wang

Shruti Nayak

4 more author(s)...
Description: This study performed a chemical genetic screen to identify PIM1 substrates in prostate cancer cells. They identified 25 previously unknown PIM1 substrates and their phosphorylation sites. Among the identified PIM1 substrates, N-Myc Downstream-Regulated Gene 1 (NDRG1) was shown to be as an inhibitor of metastasis. The study demonstrated that PIM1 phosphorylation of NDRG1 reduced its stability, nuclear...
Subject: Cancer
Access Rights: Free to All